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The first generation of Covid-19 vaccines have been highly effective and have encouraged more people to get vaccinated. But they also have limitations: their efficacy can wane without a booster shot, and they may be less effective against some variants. A recent study, however, has some positive news. Scientists at The Wistar Institute, who led the study, developed a more targeted vaccine that, in animal studies, showed stronger, broader, and more durable protection in a single, low dose.
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